Texas Instruments recommends a 4-layer PCB with a solid ground plane, and to keep the high-frequency traces short and away from the analog circuits. Additionally, use a common mode choke and ferrite beads to filter the input and output lines.
The UC2578DPTR has a thermal pad that must be connected to a heat sink or a thermal plane on the PCB. Ensure good thermal conductivity by using a thermal interface material and a heat sink with a thermal resistance of less than 10°C/W.
The maximum allowed voltage on the VCC pin is 15V. To protect against overvoltage, use a voltage regulator with overvoltage protection, such as the TLV703, and add a zener diode or a TVS diode to clamp the voltage.
Use the TI Webench tool or the UC2578DPTR datasheet's design equations to calculate the required resistor values for the desired output voltage and current. Ensure the output voltage is within the recommended range of 1.2V to 12V.
Use a low-ESR ceramic capacitor with a value of 10uF to 22uF, and a voltage rating of at least 25V. The capacitor should be placed close to the VIN pin and the GND pin.