The TXB0108DQSR can drive up to 100 pF of capacitance on each output, but it's recommended to keep the load capacitance below 50 pF for optimal performance.
To ensure signal integrity, use a solid ground plane, keep the signal traces short and away from noise sources, and use a low-ESR bypass capacitor (e.g., 0.1 μF) close to the device.
The recommended power-up sequence is to apply VCC first, followed by VCCA, and then the input signals. This ensures that the device powers up correctly and prevents latch-up.
Yes, the TXB0108DQSR is compatible with 5V systems, but ensure that the input signals do not exceed the maximum rating of 5.5V. Also, note that the device's output voltage will be limited to VCCA, which should be set to 5V or lower.
To handle hot-swapping or live insertion, use a series resistor (e.g., 1 kΩ) on the input signals to limit the inrush current and prevent damage to the device.