Texas Instruments recommends a 4-layer PCB with a solid ground plane, and to route the differential pairs as close together as possible, with a minimum of 10 mils of separation between them.
The TRS3221ECPW requires a 100-ohm differential termination resistor at the receiver end, and a 50-ohm single-ended termination resistor at the transmitter end. Additionally, the datasheet recommends using a 10-ohm series resistor at the transmitter output.
The maximum cable length supported by the TRS3221ECPW is dependent on the specific application and the type of cable used. However, as a general guideline, Texas Instruments recommends keeping the cable length under 10 meters to ensure reliable operation.
To handle common-mode noise and EMI, Texas Instruments recommends using a common-mode choke or a ferrite bead in series with the differential pairs, and to ensure good PCB layout practices such as keeping the differential pairs close together and away from noise sources.
The recommended power-up sequence for the TRS3221ECPW is to power up the VCC supply first, followed by the VCCA supply. This ensures that the internal voltage regulators are properly initialized.
TRS3221ECPW datasheet
by Texas Instruments
