The TPS2149IDGNR can sink up to 1.5A of current, but it's recommended to limit it to 1A for reliable operation.
To ensure fast switching, make sure to use a low-ESR capacitor (less than 1 ohm) and a short trace length between the capacitor and the device. Also, use a pull-up resistor (around 1k ohm) on the EN pin to ensure fast turn-on.
To minimize EMI, place the device close to the load, use a solid ground plane, and keep the input and output traces separate. Also, use a shielded inductor and orient it to minimize radiation.
The TPS2149IDGNR is rated for operation up to 125°C, but it's recommended to derate the current output by 1.5mA/°C above 85°C to ensure reliable operation.
Use a TVS diode or a zener diode on the input pin to clamp the voltage to a safe level. Also, ensure that the input capacitor is rated for the maximum input voltage.