A good PCB layout for the TOP253GN-TL should have a solid ground plane, keep the input and output traces separate, and use a star-configuration for the transformer connections. Refer to the Power Integrations application note AN-58 for more details.
To ensure reliable start-up and shutdown, make sure the input voltage is within the specified range, and the soft-start capacitor is properly sized. Also, ensure the output voltage is within the specified range during start-up and shutdown.
A common-mode choke and X-capacitors can be used to filter the input voltage. The choke should be rated for the maximum input current, and the X-capacitors should be rated for the maximum input voltage. Refer to the Power Integrations application note AN-16 for more details.
Optimize the transformer design by selecting the correct core material, wire size, and turns ratio. Use the Power Integrations transformer design tool or consult with a transformer expert to ensure optimal design.
Ensure good airflow around the device, and use a heat sink if necessary. The device has a thermal shutdown feature, but it's still important to keep the junction temperature below 150°C. Use thermal interface material and follow the recommended PCB layout to minimize thermal resistance.