The recommended operating voltage range for the SN74LVC4245ADBRE4 is 1.65V to 3.6V.
To ensure signal integrity, use a low-impedance PCB design, keep signal traces short, and use termination resistors as needed. Additionally, consider using a signal integrity analysis tool to simulate and optimize your design.
While the SN74LVC4245ADBRE4 is rated for 1.65V to 3.6V operation, it can tolerate 5V input signals. However, the output voltage will be limited to the supply voltage (VCC). If you need 5V output levels, consider using a level translator or a different device.
To avoid latch-up or other issues, ensure that the power supply voltage (VCC) is applied to all devices simultaneously, or sequence the power-on in a way that ensures the input signals are stable before the device is enabled.
The maximum clock frequency supported by the SN74LVC4245ADBRE4 is 100 MHz. However, this may vary depending on the specific application, PCB design, and operating conditions.