The maximum frequency of operation for the SN74HC112N is 35 MHz.
Yes, the SN74HC112N is compatible with 5V systems, but it's recommended to use a voltage regulator to ensure a stable 5V supply.
It's recommended to power up the VCC pin first, followed by the input signals, and power down the input signals first, followed by the VCC pin to prevent latch-up.
The recommended operating temperature range for the SN74HC112N is -40°C to 85°C.
No, the SN74HC112N is not qualified for high-reliability or aerospace applications. For such applications, consider using a radiation-hardened or high-reliability version of the device.