The PCA9542AD can support I2C bus frequencies up to 400 kHz.
Yes, the PCA9542AD can be used to switch between multiple I2C buses with different voltage levels, as long as the voltage levels are within the specified range of 1.8 V to 5.5 V.
To ensure that the PCA9542AD is properly powered down when not in use, the EN pin should be pulled low, and the VCC pin should be connected to a power source that can be switched off when not in use.
Yes, the PCA9542AD can be used in a hot-swappable application, as it has built-in protection against voltage and current surges during hot-swapping.
The PCA9542AD can drive capacitive loads up to 400 pF.