The PCA82C250T can operate in a temperature range of -40°C to 125°C.
To ensure EMC, use a shielded cable, keep the cable length as short as possible, and use a common-mode choke or ferrite bead to filter out electromagnetic interference.
Use a 4-layer PCB with a solid ground plane, keep the signal traces short and away from the power traces, and use a decoupling capacitor between VCC and GND.
Use an oscilloscope to check the signal waveforms, verify the power supply voltage, and check for short circuits or open circuits on the PCB.
Yes, the PCA82C250T is suitable for high-reliability applications, but ensure that you follow proper design and manufacturing guidelines, and perform thorough testing and validation.