The maximum frequency of operation for the M74HC4066RM13TR is 25 MHz.
Yes, the M74HC4066RM13TR is compatible with 5V systems, but it's recommended to use a voltage regulator to ensure a stable 5V supply.
It's recommended to power up the VCC pin first, followed by the input signals, and power down the input signals before the VCC pin to prevent latch-up.
The maximum current rating for the M74HC4066RM13TR is 20mA per pin, with a total current limit of 100mA for the entire device.
The M74HC4066RM13TR is rated for operation up to 125°C, but it's recommended to derate the device for high-temperature applications to ensure reliability.