The maximum operating frequency of the M74HC4053RM13TR is 10 MHz.
To ensure signal integrity, use a low-impedance output driver, minimize trace lengths, and use a ground plane to reduce noise and electromagnetic interference (EMI).
The recommended power-up sequence is to apply VCC before applying any input signals, and to ensure that all inputs are at a valid logic level before applying VCC.
To handle thermal considerations, ensure good airflow, use a heat sink if necessary, and avoid operating the device at maximum power dissipation for extended periods.
The recommended layout and routing involves keeping analog and digital signals separate, using a star topology for power and ground, and minimizing trace lengths and vias.