The maximum frequency of operation for the HEF4053BP,652 is 10 MHz.
To ensure proper switching, the control input (E) should be driven with a low-impedance source, and the voltage on the control input should be within the specified range (GND to VCC).
The maximum voltage rating for the analog signals is VCC + 0.5 V, but not exceeding 15 V.
To minimize power consumption, ensure that the device is operated within the recommended operating conditions, and consider using a lower VCC voltage if possible.
The typical on-resistance of the analog switches is around 50 ohms.