The maximum frequency of operation for the CD74HC4538E is 40 MHz.
Yes, the CD74HC4538E is compatible with 5V systems, but it's recommended to use a voltage regulator to ensure a stable 5V supply.
The output enable (OE) pin is active-low, meaning it should be connected to GND to enable the outputs. Leaving it unconnected or connecting it to VCC will disable the outputs.
The propagation delay of the CD74HC4538E is typically around 10-15 ns, but this can vary depending on the operating conditions and load capacitance.
Yes, the CD74HC4538E is compatible with 3.3V systems, but the output voltage will be limited to 3.3V. Ensure that the input signals are also 3.3V-compatible.