The maximum operating frequency of the CD74HC4053M96 is 10 MHz.
To ensure signal integrity, use a low-impedance output driver, minimize trace lengths, and use a ground plane to reduce noise and electromagnetic interference (EMI).
Yes, the CD74HC4053M96 is compatible with 5V systems, but ensure that the input voltage does not exceed the recommended maximum rating of 7V.
To avoid latch-up, ensure that the power supply voltage (VCC) is applied before the input signals, and that the input signals are stable before applying VCC.
Use a symmetrical layout, keep analog and digital traces separate, and avoid crossing analog and digital signals to minimize noise and crosstalk.