A recommended PCB layout for optimal thermal performance would be to use a 2-layer or 4-layer board with a solid ground plane on the bottom layer, and to place thermal vias under the IC to dissipate heat effectively.
To ensure stable output voltage regulation, it's essential to follow the recommended component values and layout guidelines in the datasheet, and to decouple the input and output with suitable capacitors to minimize noise and ripple.
While the datasheet specifies an operating temperature range of -40°C to 125°C, it's recommended to derate the device's performance at high ambient temperatures (above 85°C) to ensure reliable operation and prevent thermal shutdown.
The AP2145SG-13 is designed for low-dropout and low-quiescent current applications. For high-current applications, it's recommended to consider a different regulator or to use an external pass transistor to handle the high current requirements.
To protect the regulator from input voltage surges or spikes, it's recommended to add a TVS (Transient Voltage Suppressor) diode or a voltage clamp circuit at the input to limit the voltage to within the recommended operating range.